It’s no secret that the practice of medicine is complex., Comparative effectiveness research (CER) has offered an approach to evaluate the outcomes of different health care methods and identify which treatments matter most to patients. Comparative effectiveness research has the potential to inform broader health care policy conversations on value, costs, and delivery system reform.This briefing will inform attendees about the purpose and perspectives surrounding comparative effectiveness research, including how researchers conduct CER studies and how various stakeholders may utilize the results. Panelists will also explore the current CER policy landscape.