The Science Board will hear about and provide input regarding the Centers for Excellence in Regulatory Science and Innovation. The Science Board will also hear an update regarding the Scientific Computing/JANUS program. FDA’s Modernizing Toxicology Working Group will present an overview to the Science Board for input and discussion. The Center for Drug Evaluation and Research will provide their response to the May 2011 Subcommittee Report regarding the Review of the FDA/CDER Pharmacovigilance Program. The Board will be provided with an update from Subcommittee for the science review of the Center for Devices and Radiological Health.