Harvard T.H. Chan School of Public Health will host this briefing on health system change post COVID-19. The current COVID-19 pandemic has revealed a plain truth: The US health system can no longer afford to operate in silos. Instead, this once-in-a-lifetime public health crisis demands a remarkable level of cooperation across sectors and disciplines. Now more than ever, public health and business need to forge ahead together to clear the runway for our economy and society to thrive.