An investigation of the impacts of the just-released vaccine for human papilloma virus (Gardasil), the article looked at the scientific evidence behind the vaccine as well as the effects its approval had on day-to-day practice of medicine. The article uncovered concern among the medical community about both the appropriateness of Merck’s advertising campaign and the high cost (and low reimbursement) of vaccination. Experts and physicians in practice offered their advice on the vaccine could be incorporated into the practice of evidence-based medicine.