This story explores a growing body of evidence suggesting that fragments of amyloid – the protein that comprises the characteristic brain lesions of Alzheimer’s – accumulates in the lens of the eye decades before any other discernible clinical manifestation. These deposits can be clearly identified with new laser scanning devices. In the face of repeated failures of any disease-modifying therapy, Alzheimer’s researchers are focusing more on prevention. Early risk assessment and interventions to reduce risk could be the best – perhaps even the only – way to positively impact the ever-rising tide of Alzheimer’s disease. Eye exams could be an inexpensive and convenient component of such a program.
