For about 65,000 Americans with drug-resistant HIV, the development of new drugs from Merck and Pfizer are bringing about the biggest step forward in AIDS therapy since the introduction of three-drug regimens 10 years earlier. Our story showed how these and other pipelines were restocking with strong drugs capable of helping the sickest AIDS patients. Later, we were the first to report that the NIH was planning to use these drugs in an attempt to cure HIV, which has never been done.