Bird flu: Background and data overview for reporters

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photo of a wild bird next to a a colorized electron micrograph of H5N1 virus particles

Photo of a wild bird next to a colorized transmission electron micrograph of H5N1 virus particles. Photo by NIAID (CC BY 2.0)

As with covering any outbreak or other type of ongoing, developing story, it’s helpful when writing about bird flu to provide context throughout your coverage for those who have not been following it all along. Consider including some of the news developments from the list of resources at the bottom of this post in your story to provide background or a sense of the timeline for your audience.

The biology of flu viruses

All influenza A viruses have eight genes that encode 11 known proteins. The subtypes are named for the subtypes of two proteins — hemagglutinin (H) and neuraminidase (N) — that appear on the virus’s surface. There are 16 known H subtypes and 9 known N subtypes that occur in both birds and mammals. (Two additional recently identified H subtypes, H17 and H18, and N subtypes, N10 and N11, occur in bats but no other species to date.)

Although scientists have mapped out which H and N subtypes occur in different species (see two helpful pictogram charts here), the way influenza viruses can reassort, or swap, their genetic strands may enable them to infect other species as they mutate. That’s how, for example, H3N2 influenza originated in birds but then spread to dogs

Some of these combinations are regarded as low pathogenic avian influenza (LPAI) — lower risk than highly pathogenic avian influenza (HPAI). Past examples of HPAI besides H5N1 include H5N2, H5N8 and H7N9. But again, any of this can change: Some H5 and H7 LPAI have the potential to become highly pathogenic. Finally, flu A types can be divided further into different clades and sub-clades, which are groupings based on how genetically similar the viruses are.

Historical to present-day context for avian influenza

The potential for an avian influenza pandemic has been recognized since 1997, when an outbreak among people in Hong Kong with a 33% mortality rate alarmed public officials and was contained after slaughtering 1.5 million chickens. At that time, soon after the height of the AIDS pandemic, the recognition of the catastrophic potential of emerging diseases that spill over from animals to humans led to a greater public health focus on prevention rather than simply response. 

In the 2000s, when a strain related to the one that caused the outbreak in Hong Kong emerged, an apparatus for monitoring the virus’s evolution was set up. Much of the pandemic preparedness that was put in place by the late 2000s was aimed at influenza spillovers, which is why some of it failed when the next big pandemic turned out to be a coronavirus, as health security historian Andrew Lakoff, Ph.D., of UCLA detailed in his 2024 book, “Planning for the Wrong Pandemic.” 

“Ten or 15 years ago, if bird flu was infecting cattle and spreading wildly in poultry and even infecting cats, there would be a massive freak out. And there would be a lot of tracking and figuring out how to stop it,” says Lakoff. “But the political/scientific situation is different because there isn’t generalized bipartisan agreement that we should be preparing for a pandemic.”

That has become particularly evident in the current federal response to bird flu. Among the casualties of the broad cuts being made by Elon Musk’s Department of Government Efficiency (DOGE) were USDA employees working on the bird flu response. Although the agency reversed course and hoped to rehire those fired, it’s not clear how successful they were in that endeavor, and the federal response could have been hobbled in the process. Meanwhile, HHS Secretary Robert F. Kennedy Jr. has suggested simply letting the virus run wild, an approach experts roundly criticized, not least because of the increased potential for mutations.

That said, Kennedy does not have jurisdiction over USDA, which announced last month a $1 billion investment to combat highly pathogenic avian influenza (HPAI). The money is for supporting farmers with infected flocks, improving biosecurity measures to block spread from wild birds, continued vaccine development and therapeutics for chickens — but nothing toward the spread in dairy cattle. 

But it’s clear federal surveillance is inadequate for the situation at hand. Although the data published by CDC and USDA (listed below) are reliable, they are incomplete and behind. When a friend of Katie Burke’s found a dead seagull in the mountains of Floyd County, Virginia, far from where seagulls normally show up, she reported it to local wildlife authorities. They told her to dispose of it and did not test it for avian flu. Because much of the bird flu surveillance relied on federal support, local testing programs are backlogged, and avian flu cases in wild birds in the United States are undercounted. Local stories and efforts can help fill in these gaps.

Information sharing from these federal agencies has also been hobbled. As science journalist Lauren Leffer discussed in a recent interview with Nilay Patel at Decoder, experts on influenza usually communicate daily or weekly with staffers at the CDC and USDA. That information exchange is critical to evidence-based, efficient responses to pandemic prevention, and it’s not happening. The CDC has also published and then unpublished concerning data on transmission from cats to people. Although poultry farmers are motivated to test and contain outbreaks, because the disease is lethal to their livestock, dairy farmers are undertesting and underreporting. Cases in people are also undercounted. Wastewater testing offers a sense of the bigger picture in humans.

Tracking the spending of limited resources for bird flu surveillance as well as any other federal initiatives to address HPAI should provide multiple story ideas, particularly at state and local levels. In an upcoming tip sheet, we’ll suggest more specific local story ideas. 

Resources

Note: If any of these URLs no longer work due to changes from the current administration, use the Internet Archive’s Wayback Machine to find the most recently available page. Also, keep in mind, as noted above, that current surveillance is underfunded and inadequate, so these federal sources will have incomplete data, a reality that may be worth communicating to audiences in ongoing coverage. 

General information

Information on human health

Information on livestock and wild animals

Katie Burke and Tara Haelle