Health Journalism Glossary

Endocrine-disrupting chemical

  • Patient Safety

Human-made substances that interfere with human hormones and are associated with a variety of health problems. 

Deeper dive

Biomonitoring shows nearly every human has been exposed to some of the estimated 1,000 endocrine-disrupting chemicals (EDCs), which include pesticides such as the insecticide DDT, plastics such as bisphenol A (BPA), and flame retardants used in furniture and floor coverings. Exposure can occur via air, food, water, and the womb. Health problems linked to EDCs include male reproductive issues, leukemia, neurobehavioral disorders, and early female puberty. According to the Endocrine Society, many suspected EDCs have not been tested. The society’s scientific statement on EDCs, published in 2015, established that the effects of EDCs can transfer to subsequent generations and held that chemicals should be tested before being introduced into the environment.

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