How much and how well older adults sleep may be associated with Alzheimer’s disease, according to a study published in JAMA Neurology this week. Researchers from The Johns Hopkins Bloomberg School of Public Health found that buildup of ß-Amyloid plaques — one of the hallmarks of the disease — was greater in people who reported sleep disturbances and who slept for fewer hours than those who got at least seven hours of Z’s with good sleep quality.
Fluctuations in ß-Amyloid levels may be regulated by sleep-wake patterns according to the report’s authors. Investigators looked at data from 70 adults (average age 76 years) in the Baltimore Longitudinal Study of Aging. Plaque buildup was measured by imaging of the brain.
According to the National Institute on Aging, as many as 5.1 million Americans may have the disease. First symptoms usually appear after age 60, but it’s likely that damage to the brain starts a decade or more before problems are evident. Previous studies have linked disturbed sleep to cognitive impairment in older people. Continue reading